When development starts the genes are in a repressed stage. During cleavage the genes are inactive (with the exception of histone genes), and whatever hereditary traits can be observed are due to gene action during the growth and maturation of the oocyte. From gastrulation onward, some genes become activated, and the action of individual genes becomes evident. By observing normal [...]
In this article we will discuss about the control of reactive ability of tissues by the genotype. While the initial step in the differentiation of cells is made by the cytoplasm, it can be shown that the final result cannot be achieved without the involvement of hereditary factors, the nuclear genes. This is true in particular in the case of [...]
In this article we will discuss about:- 1. The Problem of Reversibility of Differentiation 2. Chemical Substances as Means of Controlling Differentiation 3. Epithelial-Mesenchymal Interactions. The Problem of Reversibility of Differentiation: Differentiation may be reversible to a certain extent. The morphological and physiological peculiarities of tissues require for their maintenance the environment which surrounds them in the normal organism. Except [...]