In this article we will discuss about:- 1. Biochemistry of Thyroid Hormone 2. Synthesis of Thyroid Hormone 3. Secretion. Biochemistry of Thyroid Hormone: Thyroid follicular cells synthesise and secrete two iodinated amino acids as hormones, viz., thyroxine or T4 or 3, 5, 3', 5'-tetraiodothyronine and T3 or 3, 5, 3'- triiodothyronine (Fig. 7.19). Instead of these hormones, the C cells [...]
In this article we will discuss about:- 1. Meaning of Thyroid Gland 2. Development of Thyroid Gland 3. Location 4. Anatomy 5. Histology and Cytology. Meaning of Thyroid Gland: Thyroid gland is the largest organ (weighing about 15-25 gm. in adult human), specialised for endocrine function in human body. This gland is capable of accumulating iodide in great excess and [...]
In this article we will discuss about:- 1. Biochemistry of Calcitonin 2. Biosynthesis of Calcitonin 3. Physiological Roles. Biochemistry of Calcitonin: Calcitonin is peptide hormone having 32 amino acid residues, with a 1-7 intrachain disulfide ring and a prolinamide carboxy-terminal group (Fig. 7.23) in human. Biosynthesis of Calcitonin: Like many other peptide hormones, it is derived from a larger precursor [...]